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Semaglutide also slows gastric emptying and increases feelings of fullness, leading to reduced calorie intake and significant weight loss

We will get definitive data on long-term weight loss sustainability, detailed body composition analysis, cardiovascular outcomes, liver fat effects at scale, and safety across diverse populations

However, one possibility does remain open to us, which is that at least some portion of the beneficial effects of 17-estradiol treatment act through inhibition of 5-reductase and reduction of DHT levels

Like with many chronic conditions, being overweight causes an imbalance in the way our bodies function